Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332328 | 0.86 | F2 (0.74) | F2 | |
| SCHEMBL8543177 | 0.84 | F2 (0.63) | F2 | |
| SCHEMBL7335262 | 0.83 | GRK2 (0.49) | F2ALDH1A1FAAHMAPK1 | |
| SCHEMBL7324955 | 0.77 | FAAH (0.50) | ALDH1A1SMN1; SMN2FAAHMAPTMAPK1 | |
| SCHEMBL8547055 | 0.77 | F2 (0.72) | F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8541190 | 0.76 | F2 (0.72) | F2 | |
| SCHEMBL8543078 | 0.76 | F2 (1.00) | F2 | |
| SCHEMBL24842383 | 0.75 | GAA (0.47) | F2ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7334463 | 0.75 | LMNA (0.67) | SMN1; SMN2MAPK1 | |
| SCHEMBL9479700 | 0.75 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2FAAHMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |