Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 3/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115032 | 0.85 | PTPN1 (0.61) | ALPGPTK2BRXRABRD4NPC1 | |
| SCHEMBL27595889 | 0.84 | SGMS2 (0.57) | NPC1MAPTL3MBTL1SGMS2PTGER1 | |
| SCHEMBL339812 | 0.83 | MAPT (0.71) | ALPGPTK2BRXRABRD4MAPT | |
| SCHEMBL5843845 | 0.82 | NPC1 (0.49) | ALPGPTK2BRXRABRD4NPC1 | |
| SCHEMBL3804975 | 0.82 | NPC1 (0.54) | ALPGPTK2BRXRABRD4NPC1 | |
| Formaldehyde SCHEMBL27831678 | 0.81 | MAPT (0.63) | ALPGPTK2BRXRABRD4MAPT | |
| SCHEMBL6026935 | 0.81 | NPC1 (0.51) | ALPGPTK2BRXRABRD4NPC1 | |
| SCHEMBL27461034 | 0.81 | TDP1 (0.52) | ALPGPTK2BRXRABRD4NPC1 | |
| SCHEMBL27276089 | 0.81 | BRD4 (0.55) | ALPGPTK2BRXRABRD4NPC1 | |
| SCHEMBL143632 | 0.81 | KDM4E (0.46) | MAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2908639-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| WO-2014060502-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| EP-2675277-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | Bayer Intellectual Property GmbH (DE) | 2013-12-25 | — | — | EP | disclosed |
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-28 | — | — | US | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| WO-2012110517-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER CROPSCIENCE AG (DE) | 2012-08-23 | — | — | WO | disclosed |
| US-8198214-B2 | Solid formulation | BAYER CROPSCIENCE AG (DE) | 2012-06-12 | — | — | US | disclosed |
| US-6235680-B1 | REDUCING SIDE EFFECT OF PESTICIDE | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-22 | — | — | US | disclosed |
| US-5972839-A | MIXTURE WITH PLANT SAFENING AGENT | HOECHST SCHERING AGREVO GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5756422-A | PLANT SAFENING AGENTS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5739079-A | CEREAL, RICE, CORN CROP SAFENER MIXED WITH WEED HERBICIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5733847-A | Selective herbicidal compositions in the form of concentrated microemulsions | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-31 | — | — | US | disclosed |
| US-5698539-A | PLANT SAFENING AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| US-5536698-A | Crop-protecting compositions containing isoxazolines or isothiazdines, novel isoxazolines, and their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5516750-A | FOR PESTICIDES AND HERBICIDES IN CROP PLANTS | HOECHST SCHERING AGREVO GMBH (DE) | 1996-05-14 | — | — | US | disclosed |
| US-5380852-A | Plant safening agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| US-4613677-A | One-step hydrogenation/esterification of benzyloxy phenoxy propanoic acid | STAUFFER CHEMICAL COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | ALPG 4014/4885PTK2B 4540/4885RXRA 819/4885 |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | AADAC, PFAS, CBR3 | ALPG 1105/4885PTK2B 2406/4885RXRA 3338/4885 |
| US-20130316901-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | DDT, ING2, DNER | ALPG 1366/4885PTK2B 2065/4885RXRA 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.