Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567758 | 0.73 | ALDH1A1 (0.49) | ACE | |
| SCHEMBL7371673 | 0.72 | ITGB3 (0.51) | ITGB3ITGA2BACE | |
| SCHEMBL2565333 | 0.70 | ACE (0.49) | ITGB3ITGA2BACE | |
| SCHEMBL7449486 | 0.67 | TBXAS1 (0.56) | TBXAS1FNTAFNTBHTR2BALOX15 | |
| SCHEMBL4655987 | 0.67 | TBXAS1 (0.97) | TBXAS1 | |
| SCHEMBL11009198 | 0.66 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL7051672 | 0.66 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL1460951 | 0.66 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL28703772 | 0.66 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL1091991 | 0.66 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |