Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HCN1 | O60741 | 1/20 | 0.32 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7335533 | 0.89 | ABCB1 (0.34) | HCN1HCN4AVPR2AVPR1AAVPR1B | |
| SCHEMBL7346091 | 0.88 | HCN1 (0.35) | HCN1HCN4AVPR2AVPR1AAVPR1B | |
| SCHEMBL7342040 | 0.87 | LMNA (0.37) | MAPTALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL7778661 | 0.87 | LMNA (0.37) | MAPTALDH1A1TP53ADRA1DADRA1A | |
| SCHEMBL7337544 | 0.87 | AVPR2 (0.40) | MAPTPKMTDP1ALDH1A1AVPR2 | |
| SCHEMBL7420333 | 0.87 | CYP3A4 (0.34) | HCN1HCN4AVPR2AVPR1AAVPR1B | |
| SCHEMBL7337579 | 0.85 | AVPR2 (0.34) | MAPTPKMTDP1ALDH1A1AVPR2 | |
| SCHEMBL7962148 | 0.84 | IRAK4 (0.34) | HCN1HCN4AVPR2AVPR1AAVPR1B | |
| SCHEMBL7338649 | 0.84 | AVPR2 (0.36) | MAPTAVPR2AVPR1AAVPR1BTP53 | |
| Hydrochloric Acid SCHEMBL7424661 | 0.84 | IRAK4 (0.33) | HCN1HCN4AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |