Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92943 | 0.86 | KDM4C (0.41) | KDM4CDHFRCREBBPEP300ICAM1 | |
| SCHEMBL16318881 | 0.86 | KDM4C (0.41) | KDM4CDHFRCREBBPEP300ICAM1 | |
| SCHEMBL1732627 | 0.86 | KDM4C (0.41) | KDM4CDHFRCREBBPEP300ICAM1 | |
| SCHEMBL2849400 | 0.85 | ICAM1 (0.42) | KDM4CDHFRCREBBPEP300ICAM1 | |
| SCHEMBL23662562 | 0.83 | DHFR (0.43) | KDM4CDHFRCREBBPEP300ICAM1 | |
| SCHEMBL10214541 | 0.83 | L3MBTL1 (0.47) | KDM4CL3MBTL1TACR1LMNA | |
| SCHEMBL29865973 | 0.83 | CA2 (0.45) | KDM4CDHFRCA1CA2 | |
| SCHEMBL7852875 | 0.83 | CA2 (0.45) | KDM4CDHFRCA1CA2 | |
| SCHEMBL2767753 | 0.83 | CYP4F2 (0.46) | KDM4CDHFRCREBBPEP300ICAM1 | |
| SCHEMBL92954 | 0.82 | NAAA (0.47) | KDM4CCREBBPEP300MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543517-A | VIRICIDES | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-08-06 | — | — | US | disclosed |