Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 15/20 | 0.50 |
| ▸ | ACE | P12821 | 10/20 | 0.50 |
| ▸ | CPA1 | P15085 | 10/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310028 | 1.00 | MME (0.50) | MMEACECPA1ACE2GPR88 | |
| SCHEMBL7333784 | 0.85 | CPA3 (0.52) | MMEACEGPR88 | |
| SCHEMBL7315467 | 0.85 | CPA3 (0.52) | MMEACEGPR88 | |
| SCHEMBL7323948 | 0.85 | CPA3 (0.52) | MMEACEGPR88 | |
| SCHEMBL7313773 | 0.85 | CPA3 (0.52) | MMEACEGPR88 | |
| SCHEMBL8641283 | 0.77 | MME (0.66) | MMEACECPA1ACE2GPR88 | |
| SCHEMBL7315209 | 0.77 | PTGS2 (0.40) | MMEACECPA1ACE2 | |
| SCHEMBL7312449 | 0.77 | CPA3 (0.43) | MMEACE | |
| SCHEMBL10883595 | 0.75 | ALPI (0.56) | — | |
| SCHEMBL7315216 | 0.75 | ECE1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866604-A | Thiol derivatives with metallopeptidase inhibitory activity | ZAMBON GROUP S.P.A. (IT) | 1999-02-02 | — | — | US | disclosed |
| US-5760241-A | ANGIOTENSIN CONVERTING ENZYME AND ENKEPHALINASE INHIBITORS; CARDIOVASCULAR DISORDERS | ZAMBON GROUP S.P.A. (IT) | 1998-06-02 | — | — | US | disclosed |