Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342630 | 0.87 | ACACB (0.44) | NPC1ALDH1A1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL7342688 | 0.85 | PTPN1 (0.46) | MAOBRAB9APTPN1YAP1 | |
| SCHEMBL7338794 | 0.85 | ITGA4 (0.39) | TSHRNPC1RAB9A | |
| SCHEMBL7345626 | 0.81 | SIRT2 (0.45) | NPC1RAB9ASMN1; SMN2PTPN1YAP1 | |
| SCHEMBL6185955 | 0.77 | LTA4H (0.47) | MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28666508 | 0.76 | IDO1 (0.34) | — | |
| SCHEMBL28666510 | 0.76 | IDO1 (0.34) | — | |
| SCHEMBL7339224 | 0.76 | PTPN1 (0.46) | MAOBGPR132PTPN1 | |
| SCHEMBL7339216 | 0.76 | PTPN1 (0.46) | MAOBGPR132PTPN1 | |
| SCHEMBL4600305 | 0.75 | PPARG (0.39) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |