Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342630 | 0.83 | ACACB (0.44) | YAP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7342688 | 0.83 | PTPN1 (0.46) | PTPN1LTA4HYAP1RAB9AFFAR1 | |
| SCHEMBL7339208 | 0.81 | MAOB (0.45) | PTPN1YAP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7338794 | 0.81 | ITGA4 (0.39) | NPC1RAB9ABACE1 | |
| SCHEMBL4599009 | 0.80 | PPARG (0.42) | PTPN1HDAC8IDO1 | |
| SCHEMBL7345636 | 0.79 | PTPN1 (0.49) | SIRT2PTPN1YAP1HDAC8BCL2 | |
| SCHEMBL7345627 | 0.79 | PTPN1 (0.49) | SIRT2PTPN1YAP1HDAC8BCL2 | |
| SCHEMBL6185955 | 0.78 | LTA4H (0.47) | LTA4HNPC1RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL7342695 | 0.77 | LTA4H (0.55) | SIRT2PTPN1LTA4HAURKARPS6KB1 | |
| SCHEMBL7342701 | 0.77 | LTA4H (0.55) | SIRT2PTPN1LTA4HAURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |