Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.43 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.38 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339208 | 0.87 | MAOB (0.45) | ACACBGPR132YAP1MAPK1NPC1 | |
| SCHEMBL7342688 | 0.85 | PTPN1 (0.46) | YAP1RAB9A | |
| SCHEMBL7345626 | 0.83 | SIRT2 (0.45) | YAP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7338794 | 0.83 | ITGA4 (0.39) | NPC1RAB9A | |
| SCHEMBL6185955 | 0.80 | LTA4H (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7342642 | 0.77 | GPR132 (0.49) | ACACBGPR132CMKLR2CMKLR1YAP1 | |
| SCHEMBL7342635 | 0.77 | GPR132 (0.49) | ACACBGPR132CMKLR2CMKLR1YAP1 | |
| SCHEMBL28666510 | 0.75 | IDO1 (0.34) | — | |
| SCHEMBL28666508 | 0.75 | IDO1 (0.34) | — | |
| SCHEMBL7337394 | 0.74 | ACACB (0.56) | ACACBGPR132MMP13CMKLR2CMKLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |