Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342630 | 0.85 | ACACB (0.44) | YAP1RAB9A | |
| SCHEMBL7339208 | 0.85 | MAOB (0.45) | PTPN1MAOBYAP1RAB9A | |
| SCHEMBL7338794 | 0.85 | ITGA4 (0.39) | RAB9A | |
| SCHEMBL7345626 | 0.83 | SIRT2 (0.45) | PTPN1YAP1RAB9ALTA4HBCL2 | |
| SCHEMBL6185955 | 0.81 | LTA4H (0.47) | MAOBRAB9ALTA4HFFAR1 | |
| SCHEMBL7342697 | 0.77 | PTPN1 (0.57) | PTPN1YAP1P2RX7ABCB1GPR34 | |
| SCHEMBL7342692 | 0.77 | PTPN1 (0.57) | PTPN1YAP1P2RX7ABCB1GPR34 | |
| SCHEMBL28666508 | 0.76 | IDO1 (0.34) | ABCB1 | |
| SCHEMBL28666510 | 0.76 | IDO1 (0.34) | ABCB1 | |
| SCHEMBL4600305 | 0.75 | PPARG (0.39) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |