Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.79 |
| ▸ | NPC1 | O15118 | 11/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.79 |
| ▸ | HTT | P42858 | 6/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MITF | O75030 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345303 | 0.89 | ALDH1A1 (1.00) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL7338508 | 0.78 | NPC1 (0.71) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL7341997 | 0.78 | NPC1 (0.71) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL1507876 | 0.77 | ALDH1A1 (0.64) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL7342035 | 0.77 | NPC1 (0.79) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL7339073 | 0.77 | ALDH1A1 (0.69) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL7339786 | 0.77 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL20681654 | 0.77 | NPC1 (0.63) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL4819693 | 0.76 | NPC1 (0.68) | RAB9ANPC1ALDH1A1KMT2AHTT | |
| SCHEMBL10400233 | 0.76 | ALDH1A1 (0.73) | RAB9ANPC1ALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |