Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390268 | 0.81 | CYP2D6 (0.42) | — | |
| Hydrochloric Acid SCHEMBL8394416 | 0.80 | KMT2A (0.40) | LMNASMN1; SMN2FGFR1FGFR2FGFR4 | |
| SCHEMBL7343207 | 0.78 | CTSK (0.50) | ELANE | |
| SCHEMBL7339604 | 0.78 | CTSK (0.50) | ELANE | |
| SCHEMBL7337140 | 0.77 | CTSL (0.53) | — | |
| SCHEMBL7337277 | 0.76 | CTSK (0.59) | — | |
| SCHEMBL14932686 | 0.73 | CTSS (0.52) | — | |
| SCHEMBL5350533 | 0.73 | CTSS (0.52) | — | |
| Hydrochloric Acid SCHEMBL7337126 | 0.71 | ALDH1A1 (0.41) | LMNAFGFR1SRCFGFR2FGFR4 | |
| SCHEMBL8399106 | 0.67 | KDM1A (0.34) | SMN1; SMN2TDP1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590650-B1 | Cyclopropene derivatives with thiol protease inhibiting activity | MITSUBISHI CHEM CORP (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5395958-A | Intermediates for enzyme inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0590650-A1 | Cyclopropene derivatives with thiol protease inhibiting activity | Mitsubishi Chemical Corporation (JP) | 1994-04-06 | — | — | EP | disclosed |