Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341957 | 0.85 | PLG (0.50) | TACR2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7335392 | 0.85 | TACR2 (0.56) | TACR2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7337265 | 0.84 | TACR2 (0.56) | TACR2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7342765 | 0.84 | PLG (0.61) | PLGPRSS1PRSS2PRSS3REN | |
| SCHEMBL7341933 | 0.83 | PPARG (0.50) | CTSSCTSKTACR2PLGPRSS1 | |
| SCHEMBL7345736 | 0.83 | REN (0.51) | CTSSPLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7339691 | 0.83 | CTSS (0.56) | QPCTCTSSCTSKTACR2ALDH1A1 | |
| SCHEMBL7343283 | 0.82 | ALDH1A1 (0.50) | CTSSCTSKALDH1A1PPARG | |
| SCHEMBL7345870 | 0.82 | TACR2 (0.50) | CTSSTACR2PLGPRSS1PRSS2 | |
| SCHEMBL7337025 | 0.82 | KLKB1 (0.52) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |