Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.55 |
| ▸ | MMP8 | P22894 | 5/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 11/20 | 0.52 |
| ▸ | MMP9 | P14780 | 11/20 | 0.52 |
| ▸ | MMP3 | P08254 | 4/20 | 0.52 |
| ▸ | BMP1 | P13497 | 7/20 | 0.50 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6412975 | 0.99 | MMP13 (0.54) | MMP13MMP8MMP1MMP7MMP12 | |
| SCHEMBL26772448 | 0.86 | MMP9 (0.55) | MMP13MMP8MMP2MMP9BMP1 | |
| Hydrochloric Acid SCHEMBL6419241 | 0.85 | MMP9 (0.54) | MMP13MMP8MMP2MMP9BMP1 | |
| Hydrochloric Acid SCHEMBL6416157 | 0.84 | MMP9 (0.67) | MMP13MMP8MMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL7347721 | 0.84 | MMP2 (0.50) | MMP13MMP8MMP1MMP7MMP12 | |
| Hydrochloric Acid SCHEMBL6416821 | 0.83 | BMP1 (0.48) | MMP13MMP8MMP1MMP7MMP12 | |
| Hydrochloric Acid SCHEMBL7349346 | 0.80 | BMP1 (0.66) | MMP8MMP1BMP1 | |
| Hydrochloric Acid SCHEMBL7366287 | 0.79 | MMP13 (0.56) | MMP13MMP8MMP1MMP7MMP12 | |
| SCHEMBL6434395 | 0.77 | MMP3 (0.57) | MMP13MMP8MMP1MMP7MMP12 | |
| SCHEMBL26769799 | 0.76 | MMP2 (0.47) | MMP13MMP8MMP2MMP9BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606046-B1 | Arylsulfonamido-substituted hydroxamic acids | CIBA GEIGY AG (CH) | 1997-10-08 | — | — | EP | disclosed |
| EP-0606046-A1 | Arylsulfonamido-substituted hydroxamic acids | CIBA-GEIGY AG (CH) | 1994-07-13 | — | — | EP | disclosed |