Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688471 | 1.00 | CTSG (0.49) | CTSGCMA1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL8065739 | 0.99 | CTSG (0.48) | CTSGCMA1ALDH1A1CA12CA1 | |
| SCHEMBL31369895 | 0.87 | MTNR1A (0.52) | ALDH1A1KMT2AMEN1HPGDHTT | |
| SCHEMBL6843513 | 0.87 | CTSG (0.50) | CTSGCMA1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL7335341 | 0.82 | PTGES (0.45) | ALDH1A1KMT2AMEN1ATMKDM4E | |
| SCHEMBL7331445 | 0.81 | ALDH1A1 (0.51) | CTSGCMA1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL8959813 | 0.80 | ALDH1A1 (0.50) | CTSGCMA1ALDH1A1CA12CA1 | |
| SCHEMBL21715383 | 0.77 | MMP12 (0.48) | CTSGCMA1ALDH1A1CA12CA1 | |
| SCHEMBL30753443 | 0.77 | MMP12 (0.48) | CTSGCMA1ALDH1A1CA12CA1 | |
| SCHEMBL30753444 | 0.77 | MMP12 (0.48) | CTSGCMA1ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788472-A1 | A PROCESS FOR THE PREPARATION OF 5,6-DIHYDROXY-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES | CHIESI FARMACEUTICI S.p.A. (IT) | 1997-08-13 | — | — | EP | disclosed |
| WO-1995029147-A1 | A PROCESS FOR THE PREPARATION OF 5,6-DIHYDROXY-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 1995-11-02 | — | — | WO | disclosed |