SCHEMBL734093

SCHEMBL734093

C=C(C)C(=O)OCCC([SiH3])(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419928 0.89 TSHR (0.51) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28396649 0.88 TSHR (0.54) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL26918774 0.86 TSHR (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1024052 0.86 TSHR (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL21066745 0.86 TSHR (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23923096 0.86 TSHR (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL21066702 0.86 TSHR (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9469051 0.85 TSHR (0.45) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL396936 0.84 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9469046 0.84 TSHR (0.41) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
US-12030973-B2 Thermoplastic resin composition and molded article of same TECHNO-UMG CO., LTD. (JP) 2024-07-09 US disclosed
US-20240092961-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TECHNO-UMG CO., LTD. (JP) 2024-03-21 US disclosed
US-20240052165-A1 RESIN COMPOSITION AND MOLDED BODY MITSUBISHI CHEMICAL CORPORATION (JP) 2024-02-15 US disclosed
EP-4317229-A1 POLYORGANOSILOXANE-CONTAINING POLYMER, COMPOSITION, AND MOLDED ARTICLE Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
EP-4317310-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE Techno-UMG Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-4317309-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-4317325-A1 RESIN COMPOSITION AND MOLDED BODY Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
US-20230416441-A1 POLYORGANOSILOXANE-CONTAINING POLYMER, COMPOSITION, AND MOLDED ARTICLE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-12-28 US disclosed
EP-3760656-B1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER POWDER, AND RESIN COMPOSITION USING THE SAME, AND MOLDED ARTICLE FORMED OF THE SAME MITSUBISHI CHEM CORP (JP) 2023-12-27 EP disclosed
US-4994522-A Blends with polysiloxane rubbers which also have grafted acrylic ester monomers; impact strength, moldings MITSUBISHI RAYON COMPANY LIMITED (JP) 1991-02-19 US disclosed
US-4918132-A Thermoplastic polyester resin composition MITSUBISHI RAYON COMPANY LIMITED (JP) 1990-04-17 US disclosed
US-4894415-A BLENDS, FRAFT COPOLYMERS, POLYALKYL (METH)ACRYLATE MITSUBISHI RAYON CO., LTD. (JP) 1990-01-16 US disclosed
US-4892900-A CONTAINING POLYSILOXANE GRAFT POLYMER, IMPROVED IMPACT STRENGTH MITSUBISHI RAYON CO., LTD. (JP) 1990-01-09 US disclosed
US-4888388-A BLENDS WITH POLYESTERS AND GRAFTED POLYSILOXANE-ACRYLIC POLYMERS MITSUBISHI RAYON COMPANY LIMITED (JP) 1989-12-19 US disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed
US-4775712-A BLENDS WITH POLYSILOXANES-IMPACT STRENGTH, HEAT AND COLD RESISTANT, WEATHERPROOFING-MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1988-10-04 US disclosed
US-4690986-A Impact-resistant thermoplastic polyorganosiloxane-based graft copolymer and process for producing same MITSUBISHI RAYON CO., LTD. (JP) 1987-09-01 US disclosed
EP-0231776-A1 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1987-08-12 EP disclosed