SCHEMBL419928

SCHEMBL419928

C=C(C)C(=O)OCCCC([SiH3])(OC)OC

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
THRB P10828 1/20 0.44
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28396649 0.95 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL21066702 0.93 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1024052 0.93 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL21066745 0.93 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL26918774 0.93 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23923096 0.93 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL734093 0.89 THRB (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5199000 0.89 TSHR (0.42) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35614 0.85 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4358822 0.84 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1076 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN claimed
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN claimed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN claimed
CN-111607227-B Three-dimensional nano carbon/polyimide composite aerogel material and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-02-28 CN claimed
CN-115561966-A Chemical amplification type negative photosensitive polyimide coating adhesive and application 明士(北京)新材料开发有限公司 2023-01-03 CN claimed
CN-114995060-B Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-11-01 CN claimed
CN-114874441-B Chemical amplification type positive photosensitive polyimide coating adhesive and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-11-01 CN claimed
CN-114995060-A Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-09-02 CN claimed
CN-114995061-A Low-water-absorption positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-09-02 CN claimed
CN-114874441-A Chemical amplification type positive photosensitive polyimide coating adhesive and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-08-09 CN claimed
US-20040229160-A1 Novel photosensitive resin compositions ARCH SPECIALTY CHEMICALS, INC. 2004-11-18 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
US-6638617-B2 Smokeless, flameproofing and flexible multilayer insulators used as coverings for wires comprising mixtures of halogen-free thermoplastic resins and organic silicon compounds JUDD WIRE, INC. 2003-10-28 US claimed
US-20020096356-A1 Dual layer insulation system KIM YOUNG JOON (US) 2002-07-25 US claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
US-6169149-B1 EMULSION POLYMERIZATION OF AN AQUEOUS DISPERSION OF SILICONE RUBBER PARTICLES OF SPECIFIED SIZE WITH ACRYLATE RUBBER MONOMERS FOLLOWED BY GRAFTING WITH ALKENYL CONTAINING MATERIAL; IMPACT MODIFIERS WHICH ENHANCE WEATHER RESISTANCE GENERAL ELECTRIC COMPANY 2001-01-02 US claimed
US-5616753-A Stabilizers for unsaturated, polymerizable organosilicon compounds OSI SPECIALTIES, INC. (US) 1997-04-01 US claimed
US-5589219-A POLYOLEFIN INSULATING COATING SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1996-12-31 US claimed
EP-0474252-B1 Flame-retardant resin composition and insulated electrical wire employing the same SUMITOMO ELECTRIC INDUSTRIES (JP) 1995-05-24 EP claimed
US-5236985-A Obtained by irradiating with ionizing radiation composition of thermoplastic resin, magnesium hydroxide, organosilicon compound containing acrylic group SUMITOMO ELECTRIC INDUSTRIES LTD. (JP) 1993-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885THRB 4533/4885POLB 2487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.