Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.52 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306054 | 0.82 | MEN1 (0.55) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL2481197 | 0.81 | ALDH1A1 (0.54) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL19747087 | 0.80 | MAPT (0.60) | KMT2AMEN1GAAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1781701 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL7163455 | 0.79 | RAB9A (0.63) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL4435163 | 0.78 | ALDH1A1 (0.69) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL12790129 | 0.77 | KMT2A (0.64) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL182738 | 0.77 | LMNA (0.67) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL6865288 | 0.77 | SNCA (0.72) | KMT2AMEN1GAAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL29512216 | 0.77 | ALDH1A1 (0.67) | KMT2AMEN1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461047-A | Analgesics and treats prostaglandin-E2 mediated diseases in animals | G. D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |