Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350850 | 0.91 | CNR2 (0.48) | CNR2CNR1DRD4ALDH1A1POLB | |
| SCHEMBL7340750 | 0.89 | MEN1 (0.45) | CNR2CNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7339673 | 0.88 | LMNA (0.46) | CNR2CNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7342337 | 0.88 | MEN1 (0.44) | CNR2CNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7342306 | 0.88 | MEN1 (0.56) | CNR2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL7339267 | 0.87 | BCL2A1 (0.57) | CNR2DRD4DRD2MEN1KMT2A | |
| SCHEMBL7346461 | 0.86 | OPRM1 (0.53) | MEN1KMT2AALDH1A1MAPTOPRM1 | |
| SCHEMBL7347840 | 0.81 | MAPT (0.50) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7341990 | 0.80 | ALDH1A1 (0.59) | DRD4MEN1KMT2AALDH1A1POLB | |
| SCHEMBL7340748 | 0.80 | HDAC1 (0.51) | CNR2DRD4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |