Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347126 | 0.89 | HDAC1 (0.49) | HDAC1HDAC8HDAC6ALDH1A1NPC1 | |
| SCHEMBL7341991 | 0.87 | HDAC1 (0.47) | HDAC1HDAC8HDAC6ALDH1A1RAB9A | |
| SCHEMBL7339673 | 0.86 | LMNA (0.46) | HDAC1HDAC8HDAC6ALDH1A1KDM4E | |
| SCHEMBL7342306 | 0.82 | MEN1 (0.56) | ALDH1A1NPC1HTTRAB9APAX8 | |
| SCHEMBL7340750 | 0.81 | MEN1 (0.45) | HDAC1HDAC8HDAC6ALDH1A1KDM4E | |
| SCHEMBL7347705 | 0.80 | TRPM8 (0.47) | HDAC1HDAC8HDAC6ALDH1A1KDM4E | |
| SCHEMBL7342337 | 0.80 | MEN1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1KDM4E | |
| SCHEMBL7340970 | 0.80 | CNR2 (0.56) | HDAC1HDAC8HDAC6ALDH1A1KDM4E | |
| SCHEMBL4491465 | 0.79 | DRD4 (0.49) | ALDH1A1NPC1RAB9AKDM4ETSHR | |
| SCHEMBL7341990 | 0.79 | ALDH1A1 (0.59) | HDAC1HDAC8HDAC6ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |