Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733625 | 0.89 | MTNR1A (0.48) | MEN1KMT2AMTNR1AMTNR1BOPRM1 | |
| SCHEMBL734401 | 0.86 | OPRM1 (0.50) | PABPC1ALOX15MTNR1AMTNR1BOPRM1 | |
| SCHEMBL734526 | 0.82 | EGFR (0.47) | OPRM1OPRL1 | |
| SCHEMBL734295 | 0.82 | KDM4E (0.47) | OPRM1OPRL1 | |
| SCHEMBL734734 | 0.82 | ALDH1A1 (0.43) | OPRM1OPRL1 | |
| SCHEMBL736019 | 0.82 | RAD52 (0.43) | OPRM1OPRL1 | |
| SCHEMBL735840 | 0.82 | KMT2A (0.46) | MEN1KMT2A | |
| SCHEMBL735878 | 0.81 | KDM4E (0.47) | OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL734002 | 0.81 | RAD52 (0.42) | OPRM1OPRL1 | |
| SCHEMBL735512 | 0.81 | OPRM1 (0.44) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138187-B2 | Substituted heteroaryl derivatives | GRUENENTHAL GMBH (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | GRUNENTHAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | CYP3A43, HMGCR, ABCG2 | MEN1 2253/4885KMT2A 2453/4885PABPC1 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.