Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.42 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.42 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.42 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.42 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.42 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308004 | 0.86 | USP30 (0.54) | USP30MMEACEACE2ADCY6 | |
| SCHEMBL7343580 | 0.78 | MCHR1 (0.42) | MMETP53MAPTCYP1A2ANPEP | |
| SCHEMBL7322706 | 0.77 | MME (0.59) | MMEACEACE2CPA1 | |
| SCHEMBL7348036 | 0.77 | MME (0.59) | MMEACEACE2CPA1 | |
| SCHEMBL7315625 | 0.74 | USP30 (0.48) | USP30ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL7412452 | 0.73 | HDAC1 (0.52) | MMEACEACE2CPA1CYP2C9 | |
| SCHEMBL7318671 | 0.73 | HDAC1 (0.52) | MMEACEACE2CPA1CYP2C9 | |
| SCHEMBL7309944 | 0.73 | MMEL1 (0.61) | MMEACEADCY6ADCY3ADCY9 | |
| SCHEMBL28291198 | 0.72 | TP53 (0.52) | TP53MAPTCYP1A2 | |
| SCHEMBL7308495 | 0.69 | CTSS (0.52) | ADCY6ADCY3ADCY9ADCY5ADCY8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |