Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 10/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353966 | 0.86 | ACKR3 (0.38) | ACKR3MAP2K2MAP2K1 | |
| SCHEMBL7357845 | 0.83 | ALDH1A1 (0.57) | MAPTALDH1A1HSD17B10ACKR3TSHR | |
| SCHEMBL7353407 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL7353631 | 0.81 | MAPT (0.38) | MAPTALDH1A1HSD17B10ACKR3TSHR | |
| SCHEMBL7352126 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1HSD17B10ACKR3MAP2K2 | |
| SCHEMBL7352747 | 0.75 | ALDH1A1 (0.43) | MAPTALDH1A1HSD17B10ACKR3TSHR | |
| SCHEMBL7348115 | 0.74 | DRD2 (0.47) | ALDH1A1HSD17B10ACKR3MAP2K2MAP2K1 | |
| SCHEMBL7352017 | 0.73 | DRD2 (0.44) | ALDH1A1HSD17B10ACKR3MAP2K2MAP2K1 | |
| SCHEMBL7353468 | 0.71 | ALDH1A1 (0.34) | MAPTALDH1A1HSD17B10MAP2K2MAP2K1 | |
| SCHEMBL1352151 | 0.71 | PTPN1 (0.41) | MAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |