Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352126 | 0.87 | ALDH1A1 (0.47) | DRD2ACKR3MAP2K2MAP2K1ALDH1A1 | |
| SCHEMBL7348115 | 0.86 | DRD2 (0.47) | DRD2ACKR3SIGMAR1HTR1AMAP2K2 | |
| SCHEMBL7353482 | 0.85 | DRD2 (0.44) | DRD2ACKR3SIGMAR1HTR1AADRA1B | |
| SCHEMBL7350499 | 0.83 | DRD2 (0.44) | DRD2ACKR3SIGMAR1HTR1AADRA1B | |
| SCHEMBL7351979 | 0.78 | DRD2 (0.44) | DRD2ACKR3SIGMAR1HTR1AADRA1B | |
| SCHEMBL7352192 | 0.74 | DRD2 (0.62) | DRD2SIGMAR1HTR1AADRA1BKMT2A | |
| SCHEMBL7354949 | 0.73 | HTR1A (0.34) | DRD2SIGMAR1HTR1AADRA1B | |
| SCHEMBL7344816 | 0.73 | MAPT (0.40) | ACKR3MAP2K2MAP2K1ALDH1A1KMT2A | |
| SCHEMBL7344636 | 0.72 | DRD2 (0.47) | DRD2ACKR3HTR1AALDH1A1KMT2A | |
| SCHEMBL7348412 | 0.71 | SMN1; SMN2 (0.48) | ACKR3ALDH1A1KMT2AMAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |