Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352017 | 0.87 | DRD2 (0.44) | ALDH1A1KMT2AGFERMAPK1CYP1A2 | |
| SCHEMBL7348115 | 0.85 | DRD2 (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C9HSD17B10 | |
| SCHEMBL7348412 | 0.83 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AGFERMAPK1CYP1A2 | |
| SCHEMBL7344193 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KMT2AGFERMAPK1CYP1A2 | |
| SCHEMBL7344816 | 0.79 | MAPT (0.40) | ALDH1A1KMT2AHSD17B10ACKR3MEN1 | |
| SCHEMBL12123632 | 0.75 | DRD2 (0.54) | ALDH1A1KMT2AGFERMAPK1CYP1A2 | |
| SCHEMBL7350783 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2AGFERMAPK1CYP1A2 | |
| SCHEMBL17400787 | 0.74 | MAP2K2 (0.60) | KMT2AMEN1HPGDMAP2K2MAP2K1 | |
| SCHEMBL7353407 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1KMT2ACYP1A2HSD17B10MEN1 | |
| SCHEMBL7348410 | 0.74 | ACKR3 (0.33) | ACKR3MAP2K2MAP2K1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |