Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 6/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352017 | 0.86 | DRD2 (0.44) | DRD2ACKR3MAP2K2MAP2K1HTR1A | |
| SCHEMBL7352126 | 0.85 | ALDH1A1 (0.47) | DRD2ACKR3MAP2K2MAP2K1ALDH1A1 | |
| SCHEMBL7344636 | 0.85 | DRD2 (0.47) | DRD2ACKR3HTR1ADRD3ALDH1A1 | |
| SCHEMBL7353056 | 0.84 | DRD2 (0.46) | DRD2ACKR3HTR7HTR1ADRD4 | |
| SCHEMBL7353966 | 0.79 | ACKR3 (0.38) | DRD2ACKR3HTR7MAP2K2MAP2K1 | |
| SCHEMBL7353206 | 0.79 | DRD2 (0.46) | DRD2ACKR3HTR7HTR1ADRD4 | |
| SCHEMBL7344816 | 0.74 | MAPT (0.40) | ACKR3MAP2K2MAP2K1ALDH1A1HSD17B10 | |
| SCHEMBL7354269 | 0.73 | DRD2 (0.63) | DRD2HTR7HTR1ADRD4DRD3 | |
| SCHEMBL7348281 | 0.72 | SIGMAR1 (0.34) | DRD2HTR1ADRD3SIGMAR1 | |
| SCHEMBL7353482 | 0.72 | DRD2 (0.44) | DRD2ACKR3HTR1ADRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |