Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345195 | 1.00 | KMT2A (0.57) | KMT2AMEN1ALDH1A1L3MBTL1FPR2 | |
| SCHEMBL8346050 | 1.00 | KMT2A (0.57) | KMT2AMEN1ALDH1A1L3MBTL1FPR2 | |
| SCHEMBL6801923 | 0.84 | PKM (0.57) | KMT2AMEN1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7339055 | 0.83 | SMN1; SMN2 (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL7339063 | 0.83 | SMN1; SMN2 (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL7340842 | 0.77 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2DPP4LMNA | |
| SCHEMBL7340839 | 0.77 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2DPP4LMNA | |
| SCHEMBL8635958 | 0.76 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL7336005 | 0.75 | POLB (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL7336014 | 0.75 | POLB (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |