Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345195 | 0.76 | KMT2A (0.57) | SMN1; SMN2PKMNPC1RAB9AKMT2A | |
| SCHEMBL8346050 | 0.76 | KMT2A (0.57) | SMN1; SMN2PKMNPC1RAB9AKMT2A | |
| SCHEMBL7345198 | 0.76 | KMT2A (0.57) | SMN1; SMN2PKMNPC1RAB9AKMT2A | |
| SCHEMBL3120355 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2PKMCYP2C9CYP2C19NPC1 | |
| SCHEMBL3968410 | 0.73 | MMP1 (0.42) | SMN1; SMN2PKMCYP2C9GAACYP1A2 | |
| SCHEMBL1657591 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2PKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL1657594 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2PKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL4957734 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2PKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL3009879 | 0.71 | SMN1; SMN2 (0.67) | SMN1; SMN2PKMCYP2C9CYP2C19NPC1 | |
| SCHEMBL8635913 | 0.71 | CTSS (0.44) | SMN1; SMN2PKMNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852584-A1 | PEPTIDE DERIVATIVES HAVING ENDOTHELIN RECEPTOR ANTAGONISTIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011961-A1 | PEPTIDE DERIVATIVES HAVING ENDOTHELIN RECEPTOR ANTAGONISTIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |