Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347905 | 0.90 | PPARA (0.42) | PPARACTSSCTSKKCNA5ATM | |
| SCHEMBL7354875 | 0.82 | ATM (0.43) | PPARACTSSCTSKKCNA5ATM | |
| SCHEMBL7881462 | 0.80 | PPARA (0.55) | PPARACTSSCTSKATMPPARG | |
| SCHEMBL25961089 | 0.75 | EGFR (0.43) | KCNA5 | |
| SCHEMBL31617814 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL951581 | 0.73 | TSHR (0.46) | — | |
| SCHEMBL7345285 | 0.72 | KCNA5 (0.42) | CTSSCTSKKCNA5CTSLCTSB | |
| SCHEMBL7675373 | 0.72 | ALDH1A1 (0.42) | KCNA5 | |
| SCHEMBL3499475 | 0.72 | LMNA (0.44) | KCNA5 | |
| SCHEMBL5429186 | 0.72 | ADRA1A (0.38) | KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356888-A | Elastase inhibitors | FARMITALIA CARLO ERBA (IT) | 1994-10-18 | — | — | US | disclosed |
| EP-0378604-B1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | ERBA CARLO SPA (IT) | 1994-03-02 | — | — | EP | disclosed |
| EP-0378604-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES. | ERBA CARLO SPA (IT) | 1990-07-25 | — | — | EP | disclosed |
| WO-1989010926-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-11-16 | — | — | WO | disclosed |