Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 8/20 | 0.43 |
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27507125 | 0.84 | ATM (0.45) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL7345283 | 0.82 | PPARA (0.40) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL9588404 | 0.79 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL7349815 | 0.79 | ATM (0.61) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL18481771 | 0.79 | ALDH1A1 (0.45) | KCNA5KMT2A | |
| SCHEMBL26195473 | 0.75 | KDM4E (0.43) | CTSSCTSKKCNA5MAPTPPARG | |
| SCHEMBL28296782 | 0.75 | CTSL (0.64) | CTSSCTSKCTSLACEMAPT | |
| SCHEMBL28295047 | 0.75 | CTSL (0.64) | CTSSCTSKCTSLACEMAPT | |
| SCHEMBL23877844 | 0.75 | ATM (0.46) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL16970688 | 0.75 | ATM (0.46) | ATMCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378604-B1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | ERBA CARLO SPA (IT) | 1994-03-02 | — | — | EP | claimed |
| EP-0378604-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES. | ERBA CARLO SPA (IT) | 1990-07-25 | — | — | EP | claimed |
| WO-1989010926-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-11-16 | — | — | WO | claimed |