Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345833 | 0.89 | HRH3 (0.39) | HTR7ITGB3ITGA2BHRH3DRD2 | |
| SCHEMBL8352452 | 0.76 | ITGB3 (0.39) | HTR7ITGB3ITGA2BHRH3 | |
| SCHEMBL7375519 | 0.72 | RIPK1 (0.41) | — | |
| SCHEMBL8355509 | 0.72 | HTR7 (0.44) | HTR7ITGB3ITGA2B | |
| SCHEMBL8644651 | 0.71 | ITGB3 (0.41) | HTR7ITGB3ITGA2BHRH3 | |
| SCHEMBL7349527 | 0.70 | F10 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7371295 | 0.69 | RIPK1 (0.38) | — | |
| SCHEMBL742952 | 0.69 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL8349498 | 0.69 | F10 (0.41) | HTR7ITGB3ITGA2BHRH3DRD4 | |
| SCHEMBL8351619 | 0.68 | F10 (0.41) | HTR7ITGB3ITGA2BHRH3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |