Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554007 | 0.88 | HRH3 (0.42) | ITGB3ITGA2BHTR7HRH3 | |
| SCHEMBL8352849 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BHRH3L3MBTL1LSS | |
| SCHEMBL8644651 | 0.78 | ITGB3 (0.41) | ITGB3ITGA2BHTR7HRH3F10 | |
| SCHEMBL8355474 | 0.77 | ITGB3 (0.38) | ITGB3ITGA2BHTR7L3MBTL1LSS | |
| SCHEMBL8355447 | 0.77 | POLB (0.38) | ITGB3ITGA2BAKR1C3L3MBTL1F10 | |
| SCHEMBL8356687 | 0.76 | HTR7 (0.36) | ITGB3ITGA2BHTR7HRH3LSS | |
| SCHEMBL7345827 | 0.76 | HTR7 (0.39) | ITGB3ITGA2BHTR7HRH3 | |
| SCHEMBL8352568 | 0.75 | S1PR5 (0.37) | ITGB3ITGA2BHTR7LSSF10 | |
| SCHEMBL8357014 | 0.75 | LSS (0.39) | ITGB3ITGA2BL3MBTL1LSSF10 | |
| SCHEMBL8355470 | 0.73 | F10 (0.36) | ITGB3ITGA2BHTR7F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| CN-1195348-A | New oxazolidinone derivatives, process for preparing same and medicaments contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-07 | — | — | CN | disclosed |
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |