Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345827 | 0.89 | HTR7 (0.39) | HRH3HTR7DRD4SLC6A4ITGB3 | |
| SCHEMBL7343911 | 0.78 | HRH3 (0.44) | HRH3ITGB3ITGA2B | |
| SCHEMBL8554007 | 0.77 | HRH3 (0.42) | HRH3HTR7DRD4SLC6A4ITGB3 | |
| SCHEMBL7375522 | 0.74 | GPR119 (0.36) | HRH3 | |
| SCHEMBL8644656 | 0.73 | HRH3 (0.39) | HRH3HTR7DRD4SLC6A4ITGB3 | |
| SCHEMBL7349534 | 0.71 | HRH3 (0.35) | HRH3 | |
| SCHEMBL8595580 | 0.68 | HTR7 (0.34) | HRH3HTR7DRD4SLC6A4DRD2 | |
| SCHEMBL8553302 | 0.68 | HRH3 (0.41) | HRH3ITGB3ITGA2B | |
| SCHEMBL8552786 | 0.67 | HTR2B (0.45) | HRH3ITGB3ITGA2B | |
| SCHEMBL8593632 | 0.67 | HTR2B (0.45) | HRH3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |