Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342119 | 0.92 | SGMS2 (0.46) | MEN1KMT2ASMN1; SMN2GAASGMS2 | |
| SCHEMBL7345615 | 0.92 | MAPT (0.38) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7337600 | 0.90 | RXFP1 (0.38) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL7337081 | 0.86 | ITK (0.40) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7345964 | 0.79 | LMNA (0.49) | MEN1KMT2AGAA | |
| SCHEMBL7345858 | 0.78 | KMT2A (0.41) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7338831 | 0.77 | PYGL (0.47) | MAPTMEN1KMT2AGAA | |
| SCHEMBL7342516 | 0.77 | ALDH1A1 (0.41) | MAPTMEN1KMT2AGAA | |
| SCHEMBL7344390 | 0.77 | RXFP1 (0.42) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7778277 | 0.77 | BRD4 (0.52) | MEN1KMT2AGAASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |