Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | CBX7 | O95931 | 2/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 4/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733450 | 0.78 | ALDH1A1 (0.58) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL699106 | 0.78 | IDO1 (0.48) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL27780994 | 0.78 | USP2 (0.55) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL5678507 | 0.76 | BRD4 (0.45) | GHSRADCY8SMN1; SMN2BRD4POLB | |
| SCHEMBL5675743 | 0.75 | ALDH1A1 (0.47) | GHSRADCY8BRD4ALDH1A1 | |
| SCHEMBL27780980 | 0.75 | ALDH1A1 (0.47) | IDO1MAPTLMNAALDH1A1 | |
| SCHEMBL15337230 | 0.73 | MMP2 (0.62) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL15264189 | 0.71 | IDO1 (0.63) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL14547272 | 0.71 | GHSR (0.37) | GHSRADCY8SMN1; SMN2MAPTPOLB | |
| 5-Fluoroisatin SCHEMBL734148 | 0.70 | MAOB (0.41) | IDO1CBX7CDYLCDYL2CDY1; CDY1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138187-B2 | Substituted heteroaryl derivatives | GRUENENTHAL GMBH (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | GRUNENTHAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | CYP3A43, HMGCR, ABCG2 | IDO1 2394/4885CBX7 1604/4885CDYL 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.