Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357633 | 0.92 | HTR1A (0.34) | HTR1AHTR7DRD2HTR2CHRH1 | |
| SCHEMBL7356312 | 0.89 | ALDH1A1 (0.41) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL7347174 | 0.88 | PLA2G7 (0.35) | HTR1AHTR7DRD2HTR2CHRH1 | |
| SCHEMBL7354691 | 0.85 | PLA2G7 (0.36) | HTR1AHTR7DRD2HTR2CHRH1 | |
| SCHEMBL7357619 | 0.83 | SLC6A4 (0.35) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL7352732 | 0.82 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL7350559 | 0.81 | SLC6A4 (0.40) | ALDH1A1HTR1AHTR7DRD2HTR2C | |
| SCHEMBL7356365 | 0.81 | POLB (0.34) | ALDH1A1CACNA2D1 | |
| SCHEMBL7354019 | 0.79 | SLC6A4 (0.42) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL7346888 | 0.78 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |