Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354691 | 0.90 | PLA2G7 (0.36) | PLA2G7HTR1AHTR7DRD2HTR2C | |
| SCHEMBL7352429 | 0.90 | POLB (0.32) | PLA2G7GPR139SLC6A4APLNR | |
| SCHEMBL7346809 | 0.88 | NPC1 (0.36) | PLA2G7HTR1AHTR7DRD2HTR2C | |
| SCHEMBL7357633 | 0.87 | HTR1A (0.34) | PLA2G7HTR1AHTR7DRD2HTR2C | |
| SCHEMBL7350559 | 0.86 | SLC6A4 (0.40) | PLA2G7HTR1AHTR7DRD2HTR2C | |
| SCHEMBL7349866 | 0.83 | L3MBTL1 (0.41) | — | |
| SCHEMBL7349930 | 0.82 | HTR1A (0.33) | HTR1AHTR7DRD2HTR2CSLC6A4 | |
| SCHEMBL7350636 | 0.80 | POLB (0.33) | PLA2G7HTR7HTR2CSLC6A4CACNA2D1 | |
| SCHEMBL7353677 | 0.80 | SLC6A4 (0.38) | HTR1AHTR7DRD2HTR2CSLC6A4 | |
| SCHEMBL7353137 | 0.78 | SLC6A4 (0.35) | SLC6A4APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |