Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345316 | 0.92 | NPC1 (0.34) | CALM1CAMKK2HTTSLC6A4SLC1A5 | |
| SCHEMBL7351618 | 0.87 | SLC1A5 (0.39) | CALM1CAMKK2HTTSLC6A4SLC1A5 | |
| SCHEMBL7354056 | 0.85 | SLC1A5 (0.38) | CALM1CAMKK2HTTSLC6A4SLC1A5 | |
| SCHEMBL7351672 | 0.83 | SLC6A9 (0.44) | CALM1CAMKK2SLC6A4SLC1A5MEP1B | |
| SCHEMBL7346492 | 0.80 | SLC6A4 (0.42) | SLC6A4BCHEKDM4EMEN1KMT2A | |
| SCHEMBL7353033 | 0.80 | SLC6A4 (0.36) | SLC6A4IDO1 | |
| SCHEMBL7347249 | 0.77 | HTT (0.44) | HTTSLC6A4SLC1A5KDM4EMEN1 | |
| SCHEMBL7346830 | 0.74 | SLC6A4 (0.39) | HTTSLC6A4TSHRKDM4E | |
| SCHEMBL7356394 | 0.73 | L3MBTL1 (0.44) | TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL7348152 | 0.72 | SLC6A4 (0.40) | SLC6A4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |