Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132578 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL10722736 | 0.91 | FAAH (0.48) | L3MBTL1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL10721831 | 0.91 | FAAH (0.48) | L3MBTL1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7122564 | 0.91 | FAAH (0.48) | L3MBTL1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL13013076 | 0.91 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MAPTNPC1GAA | |
| SCHEMBL1321117 | 0.89 | TSHR (0.44) | L3MBTL1ALDH1A1MAPTNPC1GAA | |
| SCHEMBL7529444 | 0.86 | KDM4E (0.39) | L3MBTL1ALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL7297373 | 0.85 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL73678 | 0.85 | NPC1 (0.38) | L3MBTL1ALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL4073047 | 0.85 | KMT2A (0.41) | L3MBTL1ALDH1A1MAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102304-B | Preparation method of N-sulfonyl substituted tetrahydroisoquinoline derivatives | UNIV ANHUI NORMAL | 2015-03-11 | — | — | CN | disclosed |
| US-8138272-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| CN-101495152-A | Preparation of polymer conjugates of vla-4 antagonists via a mitsunobu' s reaction | ELAN PHARM INC (US) | 2009-07-29 | — | — | CN | disclosed |
| EP-2019690-A2 | PREPARATION OF POLYMER CONJUGATES OF VLA-4 ANTAGONISTS VIA A MITSUNOBU'S REACTION | Elan Pharmaceuticals Inc. (US) | 2009-02-04 | — | — | EP | disclosed |
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | ELAN PHARMACEUTICALS, INC. | 2008-02-07 | — | — | US | disclosed |
| WO-2007137260-A2 | PREPARATION OF POLYMER CONJUGATES OF VLA-4 ANTAGONISTS VIA A MITSUNOBU' S REACTION | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-4407939-A | GELATIN MODIFIED WITH SUCCINIC, PHTHALIC OR TRIMELLITIC ANHYDRIDE POSITIONED BETWEEN | FUJI PHOTO FILM CO., LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4021245-A | GELATION DERIVATIVE, SILICIC ACID ANHYDRIDE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | PIGO, MANBA, OAT | L3MBTL1 3566/4885ALDH1A1 174/4885MAPT 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.