Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370478 | 0.80 | TBXAS1 (1.00) | TBXAS1LTA4HKMT2AALDH1A1KDM4E | |
| SCHEMBL15125645 | 0.80 | KMT2A (0.62) | TBXAS1KMT2AALDH1A1KDM4E | |
| SCHEMBL7989831 | 0.79 | LTA4H (0.53) | TBXAS1LTA4HHMOX1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9996050 | 0.79 | TBXAS1 (0.97) | TBXAS1LTA4HKMT2AALDH1A1KDM4E | |
| SCHEMBL16346074 | 0.79 | GSTP1 (0.66) | — | |
| SCHEMBL7842627 | 0.79 | SRC (0.81) | — | |
| Hydrochloric Acid SCHEMBL9483473 | 0.78 | KMT2A (0.70) | TBXAS1LTA4HKMT2AKDM4E | |
| SCHEMBL7132156 | 0.78 | LTA4H (1.00) | TBXAS1LTA4HHMOX1KMT2AALDH1A1 | |
| SCHEMBL5760109 | 0.78 | HMOX1 (0.65) | TBXAS1HMOX1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL7842886 | 0.78 | SRC (0.69) | TBXAS1LTA4HHMOX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993300-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0993300-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998048798-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |