Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307336 | 0.92 | PSMB5 (0.47) | ALDH1A1CYP1A2CYP2C19LCKCASP1 | |
| SCHEMBL7342412 | 0.85 | ALDH1A1 (0.49) | ALDH1A1POLBLCKHPGDL3MBTL1 | |
| SCHEMBL7348676 | 0.84 | POLB (0.52) | ALDH1A1CYP1A2CYP2C19POLBHPGD | |
| SCHEMBL7346557 | 0.81 | CTSG (0.48) | ALDH1A1POLBHPGDMAPTKMT2A | |
| SCHEMBL7346551 | 0.81 | CTSG (0.48) | ALDH1A1POLBHPGDMAPTKMT2A | |
| SCHEMBL7350634 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP2C19POLBHPGD | |
| SCHEMBL7342540 | 0.80 | PSMB5 (0.47) | ALDH1A1POLBHPGDGAAMAPT | |
| SCHEMBL7343844 | 0.80 | HPGD (0.53) | ALDH1A1CYP2C19POLBHPGDL3MBTL1 | |
| SCHEMBL7342545 | 0.80 | PSMB5 (0.47) | ALDH1A1POLBHPGDGAAMAPT | |
| SCHEMBL7348935 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C19POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603873-B1 | Aminoketone derivatives | MITSUBISHI CHEM CORP (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5424325-A | Inibitors of thiol protease and may be used as therapeutic agents for treating muscular dystrophy, cataracts, strokes | MITSUBISHI KASEI CORPORATION (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0603873-A1 | Aminoketone derivatives | Mitsubishi Chemical Corporation (JP) | 1994-06-29 | — | — | EP | disclosed |