Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348931 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBCTSLMEN1KMT2A | |
| SCHEMBL7305262 | 0.92 | PSMB5 (0.43) | POLBCTSLPSMB1PSMB5PSMB2 | |
| SCHEMBL7305254 | 0.87 | PSMB5 (0.39) | ALDH1A1POLBCTSLMEN1KMT2A | |
| SCHEMBL7348921 | 0.81 | RAB9A (0.53) | ALDH1A1POLBCTSLMEN1KMT2A | |
| SCHEMBL7348231 | 0.80 | ALDH1A1 (0.45) | ALDH1A1POLBMEN1KMT2AHPGD | |
| SCHEMBL7434956 | 0.79 | MMP3 (0.36) | ALDH1A1POLBCTSLHPGDNPC1 | |
| SCHEMBL7343836 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBCTSLMEN1KMT2A | |
| SCHEMBL7349908 | 0.79 | CAPN1 (0.61) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7349928 | 0.79 | CAPN1 (0.61) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7342412 | 0.78 | ALDH1A1 (0.49) | ALDH1A1POLBCTSLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603873-B1 | Aminoketone derivatives | MITSUBISHI CHEM CORP (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5424325-A | Inibitors of thiol protease and may be used as therapeutic agents for treating muscular dystrophy, cataracts, strokes | MITSUBISHI KASEI CORPORATION (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0603873-A1 | Aminoketone derivatives | Mitsubishi Chemical Corporation (JP) | 1994-06-29 | — | — | EP | disclosed |