Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | UGCG | Q16739 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349299 | 0.83 | MMP8 (0.38) | MMP3MMP8 | |
| SCHEMBL7356874 | 0.82 | UGCG (0.40) | MMP1UGCG | |
| SCHEMBL7352363 | 0.78 | UGCG (0.46) | ALDH1A1UGCGMEN1KMT2A | |
| SCHEMBL7348722 | 0.69 | MMP8 (0.40) | MMP8 | |
| SCHEMBL7360505 | 0.67 | MMP8 (0.50) | L3MBTL1ALDH1A1MMP1MMP3MMP9 | |
| SCHEMBL8498698 | 0.66 | L3MBTL1 (0.47) | L3MBTL1BCHEMEN1KMT2ATDP1 | |
| SCHEMBL20755330 | 0.65 | LMNA (0.35) | L3MBTL1ALDH1A1GAAUGCGMEN1 | |
| SCHEMBL7353864 | 0.64 | CSNK1E (0.48) | MMP1MMP3 | |
| Cyclohexane SCHEMBL19244609 | 0.63 | GPR84 (0.59) | — | |
| SCHEMBL22236670 | 0.63 | LMNA (0.43) | L3MBTL1ALDH1A1BCHEGAAUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009736-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | Roche Diagnostics GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011608-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-03-11 | — | — | WO | disclosed |