Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353468 | 0.86 | ALDH1A1 (0.34) | PER2PDE2AMAP2K2MAP2K1ALDH1A1 | |
| SCHEMBL7347936 | 0.86 | ALDH1A1 (0.38) | HTR1ADRD2HTR7HTR2CHRH1 | |
| SCHEMBL7352714 | 0.84 | PER2 (0.38) | HTR1ADRD2HTR7HTR2CHRH1 | |
| SCHEMBL7345096 | 0.80 | PER2 (0.38) | HTR1ADRD2HTR7HTR2CHRH1 | |
| SCHEMBL7357633 | 0.79 | HTR1A (0.34) | HTR1ADRD2HTR7HTR2CHRH1 | |
| SCHEMBL7348281 | 0.78 | SIGMAR1 (0.34) | HTR1ADRD2DRD3PDE2AHTR2A | |
| SCHEMBL7352509 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPT | |
| SCHEMBL7353966 | 0.75 | ACKR3 (0.38) | HTR1ADRD2HTR7HTR2CHRH1 | |
| SCHEMBL7351468 | 0.75 | ALDH1A1 (0.46) | HTR1ADRD2HTR7HTR2CHRH1 | |
| SCHEMBL7352557 | 0.73 | HTR1A (0.36) | HTR1AHTR2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |