Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354949 | 0.86 | HTR1A (0.34) | SIGMAR1DRD2DRD3LMNAHTR1A | |
| SCHEMBL7352557 | 0.85 | HTR1A (0.36) | SIGMAR1HTR1AHTR2ASLC6A4SLC6A3 | |
| SCHEMBL7350207 | 0.85 | SIGMAR1 (0.34) | SIGMAR1DRD2DRD3LMNAHTR1A | |
| SCHEMBL7349099 | 0.84 | HTR1A (0.39) | SIGMAR1DRD2DRD3LMNAHTR1A | |
| SCHEMBL7346136 | 0.79 | HTR1A (0.39) | SIGMAR1DRD2DRD3LMNAHTR1A | |
| SCHEMBL7348954 | 0.78 | SLC6A4 (0.32) | SIGMAR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7350899 | 0.78 | HTR1A (0.36) | DRD2DRD3HTR1AHTR2APDE2A | |
| SCHEMBL7354111 | 0.73 | HTR1A (0.56) | SIGMAR1DRD2DRD3LMNAHTR1A | |
| SCHEMBL7353468 | 0.73 | ALDH1A1 (0.34) | PDE2A | |
| SCHEMBL7348115 | 0.72 | DRD2 (0.47) | SIGMAR1DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |