Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | CCKBR | P32239 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359930 | 0.81 | ACE (0.59) | ACEMMECCKBR | |
| SCHEMBL28666844 | 0.79 | TDP1 (0.45) | ACEMME | |
| SCHEMBL8056283 | 0.77 | ACE (0.58) | ACEMMECCKBR | |
| SCHEMBL7486156 | 0.75 | CCKBR (0.72) | CCKBR | |
| SCHEMBL7486160 | 0.75 | CCKBR (0.72) | CCKBR | |
| SCHEMBL7353391 | 0.75 | ACE (0.52) | ACEMMECCKBR | |
| SCHEMBL10200771 | 0.75 | XIAP (0.56) | ACEMME | |
| SCHEMBL13259947 | 0.75 | ACE (0.49) | ACEMME | |
| SCHEMBL7312559 | 0.75 | CCKBR (0.57) | CCKBR | |
| SCHEMBL7564700 | 0.74 | CCKBR (0.63) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228854-B1 | 1-BENZAZEPINE DERIVATIVE ANTICOAGULANTS; STROKE PREVENTION | COR THERAPEUTICS, INC. | 2001-05-08 | — | — | US | disclosed |
| EP-0994894-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007731-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |