Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352732 | 0.92 | RAB9A (0.46) | L3MBTL1RAB9AKMT2ATDP1NPC1 | |
| SCHEMBL7351114 | 0.87 | L3MBTL1 (0.42) | L3MBTL1RAB9AKMT2ATDP1NPC1 | |
| SCHEMBL7356365 | 0.85 | POLB (0.34) | KMT2AMAPTALDH1A1POLBMEN1 | |
| SCHEMBL7349866 | 0.85 | L3MBTL1 (0.41) | L3MBTL1RAB9AKMT2ATDP1NPC1 | |
| SCHEMBL7352863 | 0.83 | ALDH1A1 (0.48) | L3MBTL1RAB9AKMT2ATDP1NPC1 | |
| SCHEMBL7357633 | 0.81 | HTR1A (0.34) | KMT2AHSD17B10MEN1 | |
| SCHEMBL7353033 | 0.80 | SLC6A4 (0.36) | — | |
| SCHEMBL7352509 | 0.79 | ALDH1A1 (0.44) | RAB9ANPC1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL7346830 | 0.78 | SLC6A4 (0.39) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7356312 | 0.78 | ALDH1A1 (0.41) | RAB9AKMT2ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |