Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346833 | 0.91 | MAOB (0.37) | MAOBMAOAPRKCALTB4RLTB4R2 | |
| SCHEMBL7347199 | 0.84 | MAOB (0.33) | MAOBMAOAPRKCALTB4RLTB4R2 | |
| SCHEMBL7346994 | 0.82 | TXNRD1 (0.34) | MAOBMAOASTK17B | |
| SCHEMBL6422310 | 0.82 | MTNR1A (0.36) | MAOBMAOAPRKCALMNASTK17B | |
| SCHEMBL6426238 | 0.81 | KCNA3 (0.37) | MAOBMAOAPRKCAMAPTL3MBTL1 | |
| SCHEMBL7347057 | 0.78 | STK17B (0.33) | STK17BTDP1 | |
| SCHEMBL6820565 | 0.75 | KCNA3 (0.36) | MAOBMAOAPRKCAMAPTL3MBTL1 | |
| SCHEMBL6820552 | 0.72 | STK17B (0.35) | MAOBMAOAPRKCASTK17BTDP1 | |
| SCHEMBL6826208 | 0.71 | F2RL3 (0.41) | PRKCAL3MBTL1STK17BTDP1BRD4 | |
| SCHEMBL6421978 | 0.68 | TYR (0.49) | MAOBMAOAMAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307051-B1 | UROKINASE-TYPE PLASMINOGEN ACTIVATOR ANTAGONISTS AND HAVE ANTITUMOR AND ANTIMETASTATIC ACTIVITY. | ROCHE DIAGNOSTICS GMBH (DE) | 2001-10-23 | — | — | US | disclosed |
| EP-1026165-A1 | O-substituted Hydroxycoumaranone derivatives as antitumor and antimetastatic agents | Roche Diagnostics GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |