Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 3/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353733 | 0.84 | MAOB (0.43) | MAOBMAOASTK17BLTB4RLTB4R2 | |
| SCHEMBL7346833 | 0.82 | MAOB (0.37) | MAOBMAOASTK17BTP53LTB4R | |
| SCHEMBL7346994 | 0.81 | TXNRD1 (0.34) | MAOBMAOASTK17B | |
| SCHEMBL6422310 | 0.81 | MTNR1A (0.36) | MAOBMAOASTK17BTP53PRKCA | |
| SCHEMBL6426238 | 0.80 | KCNA3 (0.37) | MAOBMAOASTK17BPRKCAMAPT | |
| SCHEMBL7347057 | 0.77 | STK17B (0.33) | STK17BMEN1KMT2ATHRB | |
| SCHEMBL6824170 | 0.74 | LMNA (0.47) | STK17BLTB4RLTB4R2PRKCAMEN1 | |
| SCHEMBL6820565 | 0.74 | KCNA3 (0.36) | MAOBMAOASTK17BPRKCAMAPT | |
| SCHEMBL6820552 | 0.71 | STK17B (0.35) | MAOBMAOASTK17BHTTPRKCA | |
| SCHEMBL6826208 | 0.70 | F2RL3 (0.41) | STK17BPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307051-B1 | UROKINASE-TYPE PLASMINOGEN ACTIVATOR ANTAGONISTS AND HAVE ANTITUMOR AND ANTIMETASTATIC ACTIVITY. | ROCHE DIAGNOSTICS GMBH (DE) | 2001-10-23 | — | — | US | disclosed |
| EP-1026165-A1 | O-substituted Hydroxycoumaranone derivatives as antitumor and antimetastatic agents | Roche Diagnostics GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |