Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360005 | 0.82 | HTR1A (0.45) | KDM4ELMNAHTR1ADRD3SIGMAR1 | |
| SCHEMBL7355240 | 0.82 | HTR1A (0.44) | MAPTKDM4EALDH1A1HTR1ADRD3 | |
| SCHEMBL7354368 | 0.81 | HTR1A (0.40) | KDM4EHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7350014 | 0.81 | HPGD (0.54) | MAPTKDM4ENPSR1HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL7357103 | 0.79 | HTR1A (0.47) | KDM4EALOX15HTR1AHSD17B10KMT2A | |
| SCHEMBL7359345 | 0.79 | HTR1A (0.47) | HTR1ASIGMAR1 | |
| SCHEMBL7360074 | 0.78 | SIGMAR1 (0.42) | KDM4EHPGDALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL7353007 | 0.78 | TRPV4 (0.45) | MAPTKDM4EUSP2ALOX15NPSR1 | |
| SCHEMBL7358512 | 0.78 | TRPV4 (0.45) | KDM4ENPSR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7359027 | 0.78 | SIGMAR1 (0.45) | KDM4ELMNAHTR1ADRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |